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Antihyperlipidemic or Dyslipidemic Drugs
Antitussives, Expectorants and Mucolytics
Sedatives and Hypnotics
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An anticoagulant is a drug that helps prevent the clotting (coagulation) of blood. These drugs tend to prevent new clots from forming or an existing clot from enlarging. They don't dissolve a blood clot. Anticoagulants are also given to certain people at risk for forming blood clots.
Anticoagulant drugs, also called anticlotting drugs or blood thinners, are available only with a physician's prescription. They come in tablet and injectable forms. They fall into three groups:
Inhibitors of clotting factor synthesis. These anticoagulants inhibit the production of certain clotting factors in the liver. One example is warfarin (brand name: coumadin).
Inhibitors of thrombin. Thrombin inhibitors interfere with blood clotting by blocking the activity of thrombin. They include heparin, lepirudin (Refludan).
Antiplatelet drugs. Antiplatelet drugs interact with platelets, which is a type of blood cell, to block platelets from aggregating into harmful clots. They include:
, ticlopidine (Ticlid), clopidogrel (Plavix), tirofiban (Aggrastat), and eptifibatide (Integrilin).
1.) Thrombosis/Deep vein thrombosis
-is the formation of a blood clot inside a blood vessel obstructing the flow of blood through the circulatory system. When a blood vessel is injured, the body uses platelets and fibrin to form a blood clot, because the first step in repairing it, is to prevent loss of blood. If that mechanism causes too much clotting, and the clot breaks free, and an embolus is formed.
- is a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body through the bloodstream. Usually this is due to embolism of a blood clot from the deep veins in the legs, a process termed venous thromboembolism.
3.)Atrial Fibrillation/Cardiac arrhythmia
-The most common cardiac arryhthmia in which the two upper chambers of the heart fibrillate instead of having a coordinated muscular contraction.
Ampalo, Alfonso jr
belongs to the class of
Oral anticoagulants (vitamin K antagonists)
Available dosage from:
Bleeding from the rectum or black stool
such as hives, a rash or itching
Swelling of the face, throat, mouth, legs, feet or hands
Bruising that comes about without an injury you remember
Haemorrhagic tendencies or blood dyscrasia
Studies in animals or human beings have demonstrated fetal abnormalities or there is evidence of fetal risk based on human experience or both, and the risk of the use of the drug in pregnant women clearly outweighs any possible benefit. The drug is contraindicated in women who are or may become pregnant.
Enoxaparin belongs to the class of Heparin and related compounds
Available dossage forms:
Common side effects:
1.bleeding that won't stop;
2.pale skin, easy bruising, unusual weakness;
3.swelling, bruising, or bleeding where an incision was made during a surgery or other medical procedure;
4.sudden numbness or weakness, headache, confusion, problems with vision, speech, or balance;
5.pain or swelling in one or both legs;
Acute bacterial endocarditis
History of ventricular arrhythmias
Severe renal impairment
Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.
Toxipen film-coated tab
Previous hypersensitivity reactions to xanthine-related products e.g. caffeine, theophylline and theobromine.
Recent cerebral and/or retinal haemorrhage
Carlos, Marites D.
Dalteparin belongs to low molecular wt heparin sodium
Irritation or pain may occur at the injection site, unusual bleeding or bruising, blood in the urine or stool, fever, Allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
Available dossage forms
available in injection, ampule
Acute gastroduodenal ulcer & cerebral hemorrhage, Severe coagulation disorders, septic endocarditis,
: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
belongs to low molecular wt heparin sodium
a bleeding stomach ulcer; uncontrolled nosebleeds; blood vessel damage in the eyes (retinopathy) caused by diabetes;
large purple spots or red pinpoint spots under your skin; bleeding from your rectum or vagina
Available dossage forms
available in injection, solution
Hypersensitivity to Na bisulfite, Generalized or focal haemorrhagic tendency, uncontrolled severe HTN,septic endocarditis.
AMPALO, Alfonso Jr.
3:00-4:00, MWF, A206
75/100 - you only included 6 drugs instead of 8
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